Abstract
Human herpesvirus (HHV)-6 and HHV-7 establish life-long latency, a hallmark of herpesviruses, reactivate frequently, and are shed in saliva. In the study on the latency and reactivation of HHV-6, we have identified the association between HHV-6 reactivation and the work-induced fatigue in healthy adults. This finding suggests that the HHV-6 reactivation can be an objective biomarker for fatigue.
