Japanese Journal of Complementary and Alternative Medicine
Online ISSN : 1348-7930
Print ISSN : 1348-7922
ISSN-L : 1348-7922
Original Article
Acute Oral Toxicity Test of Hot Water Extract of Coix lacryma-jobi L. var. ma-yuen Stapf in Rats
Hirotaka HAYASHIYasuyuki OHTATakanari ARAIYasuko SHIMANOFumihide TAKANOJeffry Michael STRONGToshiki ENOMOTOKazuo UEBABATomihisa OHTANobutaka SUZUKI
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2009 Volume 6 Issue 2 Pages 105-110


Coix lacryma-jobi L. var.ma-yuen Stapf (Coix seed) is a grass crop that has long been used in traditional medicine as a nourishing food. However, high-intake safety of the extract of the husks, pellicles and astringent skin of Coix seed has rarely been evaluated. We performed a safety test of hot water extract of all parts of Coix seed (CRD extract) in rats. CRD extract showed no significant toxicity on body weight, blood analyses, urinalysis and histopathological examination in acute toxicity tests.

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© 2009 by The Japanese Society for Complementary and Alternative Medicine
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