Abstract
The extraction of total alkaloids from Sophora alopecuroides L. was enhanced by using ion exchange resin at reduced pressure. At room temperature and 0.08 MPa vacuity for 12 h, 96% of the total alkaloids was extracted from the seed particles of 0.18–0.25 mm using deionized water of pH 3.0 in the presence of the cationic ion exchange resin 001×7 (cross-linked polystyrene, particle size 0.32–1.25 mm, exchange capacity 4.5 mmol g–1 resin, dry wt.). In contrast, it took the same time to get 72% of total alkaloids in the case without the resin. The yield of total alkaloids extracted at 0.06 MPa vacuity without the resin reached 60%, while that was only 47% in the case at normal pressure.
