Production of Bifidogenic Growth Stimulator by Co-cultivation of Propionibacterium shermanii and Lactobacillus Strain Using Lactose as a Carbon Source

Tomoaki Kouya; Masahiro Horiuchi; Kazuhiro Tobita; Katsuhiro Misawa; Eri Nakayama; Hiroyoshi Deguchi; Takaaki Tanaka; Masayuki Taniguchi

doi:10.1252/jcej.07we309

Biochemical, Food and Medical Engineering

Production of Bifidogenic Growth Stimulator by Co-cultivation of Propionibacterium shermanii and Lactobacillus Strain Using Lactose as a Carbon Source

Tomoaki Kouya, Masahiro Horiuchi, Kazuhiro Tobita, Katsuhiro Misawa, Eri Nakayama, Hiroyoshi Deguchi, Takaaki Tanaka, Masayuki Taniguchi

Author information

Tomoaki Kouya
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Masahiro Horiuchi
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Kazuhiro Tobita
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Katsuhiro Misawa
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Eri Nakayama
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Hiroyoshi Deguchi
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Takaaki Tanaka
Department of Materials Science and Technology, Faculty of Engineering, Niigata University
Masayuki Taniguchi
Department of Materials Science and Technology, Faculty of Engineering, Niigata University

Keywords: Bifidogenic Growth Stimulator, Co-cultivation, Propionibacterium shermanii, Lactobacillus, Lactic Acid

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2008 Volume 41 Issue 6 Pages 492-496

DOI https://doi.org/10.1252/jcej.07we309

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Abstract

Production of a bifidogenic growth stimulator (BGS) by propionibacterial strains was investigated using lactic acid as a carbon source. The maximum concentration (1.9 mg/L) of BGS was obtained in the mono-cultivation of Propionibacterium shermanii using 20 g/L of lactic acid. The co-cultivation, in which lactose was gradually converted only to lactic acid by a homo-fermentative lactic acid bacterium and subsequently the lactic acid was used as a carbon source for BGS production by P. shermanii, resulted in the successful BGS production. The BGS concentration obtained in the co-cultivations of P. shermanii and Lactobacillus casei or P. shermanii and Lactobacillus bulgaricus was 1.8 or 6.4 mg/L, respectively.

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