Fabrication of porous hydroxyapatite having nanometer/micrometer-size pores

Abstract

Hydroxyapatite having nanometer/micrometer-size pores was formed from the olive oil/amorphous calcium phosphate (ACP)-poly(vinyl alcohol) (PVA) gel emulsion. An ACP-PVA gel was prepared by a freeze-thaw process to form an interconnected nanoporous structure. An emulsion templating method was used to form micrometer-size pores. Nanometer/micrometer-size pores were formed from the olive oil/ACP-PVA gel emulsion. The blending of oils (olive oil/squalane) resulted in the formation of bimodal nanometer/micrometer-size pores.