Application of a Fibrinogen-based Collagen Fleece in a Neurosurgical Procedure

Abstract

A fibrinogen-based collagen fleece (TachoComb^[○!R]), was used in 21 cases during operations to assess its properties as a hemostatic modality in neurosurgical procedures and prevention of cerebrospinal fluid (CSF) leakage after duraplasty. Our clinical experience shows the efficacy of this material to control oozing hemorrhage from dural sinuses not controlled by primary hemostatic procedures. Postoperative CSF leaks developed in only one case among 16 cases that did not require operations such as lumbar CSF drainage. TachoComb^[○!R] is available to prevent CSF leaking after duraplasty.