Abstract
A nine-year-old girl with papillary meningioma in the left parietal convexity is reported. The initial size of the tumor was 6 cm in diameter and surgically removed completely. Since then, the tumor repeated recurrences six times in six years and she was surgically treated for each time. Pathological studies of each specimen resulted in papillary meningioma with typical formation of lumens by papillary cells associated with wheel formation by spindle-shape cells. MIB-1 immunohistochemistry for each specimen demonstrated initially low index at 0.4 however, the index progressively became high up to 17.5 at the sixth time. Subcutaneous tumor metastasis at the site of scalp skin flap was also recognized three times, which were surgically removed. Papillary meningioma is a rare subtype of meningioma that is categorized as grade III in WHO classification and thought to be relatively malignant in nature. The value of the MIB-1 index to predict the recurrence of tumor in benign meningioma has been well recognized. In papillary meningiomas, the risk of recurrence should be always considered regardless to the MIB- 1 index value.
