Gene Therapy for Neurological Diseases

Abstract

There is a limitation in the treatment of neurological diseases, such as neurodegenerative disease, brain tumor, and cerebrovascular disease. Gene therapy is one promising treatment for these diseases. Clinical trials have been studied for brain tumor, Canavan disease, and amyotrophic lateral sclerosis. The efficacy was proved to some extent, but there were some problems such as vector immunoreactivity. However, more effective and safe vectors have been developed recently, and gene therapy might be popular in the field of cerebral diseases in the future.