Intraoperative Photodynamic Diagnosis of Brain Tumor using a Purple Semiconductor Laser Device for a FDD Study

Abstract

We attempted intraoperative fluorescence diagnosis in a brain tumor patient who was given 5-aminolevulinic acid using a purple semiconductor laser device as part of a photodynamic diagnosis (PDD) study. The light output was able to be powerfully applied by adjusting the wavelength to 405 ± 1 nm. It was useful to be able to perform a fluorescence assisted diagnosis of his brain tumor using an optic fiber under a microscope for irradiation.