A Case of Primary Sellar Neuroblastoma

Abstract

We present an extremely rare case of primary sellar neuroblastoma. A 75-year-old woman presented with progressive visual disturbance and bitemporal hemianopsia. Magnetic resonance imaging (MRI) revealed a huge parasellar enhanced lesion that had enlarged in the course of a year. She underwent surgical resection via the endoscopic transsphenoidal approach followed by conventional radiotherapy (55Gy) and carboplatin-based chemotherapy. The tumor decreased in size in response to adjuvant therapies. We found only 9 earlier cases of primary sellar neuroblastoma in the literature. Preoperative diagnosis is difficult because primary sellar neuroblastomas have neither specific radiographic findings nor symptoms. Standard treatment has not been established to date. Although primary sellar neuroblastoma is extremely rare, it should be considered as a differential diagnosis in patients with huge, rapidly-growing parasellar tumors.