Treatments for Mild and Moderate Traumatic Brain Injury

Abstract

  The One Week Study 2012 (Japan Neurotrauma Data Bank) showed that mild or moderate traumatic brain injury accounted for 86% of neurotrauma cases requiring admission. Thus, mild or moderate traumatic brain injury are a relatively common pathological condition. The condition aggravated to a serious state and required surgical treatment in 15% of moderate cases and 7.6% of mild cases, indicating that careful judgment and management of these cases are important. After admission, it is important to maintain a resting state based on risk factors for aggravation. Blood biomarkers such as S-100B protein and D-dimer may be useful for predicting the presence of intracranial lesions and aggravation to a serious state, and we will introduce a result of our research about blood biomarkers in mild traumatic brain injury patients. The severity of neurotrauma may initially be mild or moderate, but can aggravate to a serious state that may lead to a poor outcome.

  Social problems, such as higher brain dysfunction and postconcussional syndrome, also accompany neurotrauma, which makes treatment of this injury of particular importance for neurosurgeons.