2017 Volume 26 Issue 9 Pages 668-676
Prognostic factors for patients with brain metastases vary by diagnosis, implying considerable heterogeneity in outcome even within a single tumor type. Evidence-based clinical practice guidelines have rapidly evolved into critically important tools for optimizing individualized care for patients. Guidelines have become particularly relevant for the treatment of brain metastasis given the importance of the multidisciplinary coordination of care with neuro-oncology and radiation oncology, in addition to neurosurgery. Our clinical practice guideline 2016 can help by providing a starting point where a systematic evidence review leads to practice recommendations formulated by a multidisciplinary panel of experts. Partial updating is now in progress, and must be followed by full updating with the GRADE system.