2020 Volume 29 Issue 12 Pages 864-868
Pipeline embolization device (PED) has grown in popularity as an alternative to both microsurgery and coil embolization for the treatment of large unruptured symptomatic internal carotid artery (ICA) aneurysms. However, little is known about its efficacy.
We retrospectively evaluated patients with compressional symptoms caused by large unruptured ICA aneurysms who underwent endovascular treatment with the PED at our institution from January 2016 to September 2018. During the 12-month clinical follow-up, 10 patients (55.6%) had resolution or significant improvement of their cranial neuropathies.
Patients who received treatment with PED within 180 days after onset were significantly more likely to demonstrate neurological improvement at follow-up (OR 56 ; 95%CI 2.93-1071.69).
Endovascular treatment with PED for symptomatic ICA aneurysm is useful for improving neurological symptoms. Time from onset to treatment appears to be an important factor for good neurological outcome.