2022 Volume 31 Issue 11 Pages 693-700
Transsphenoidal surgery (TSS) is the first-choice treatment for the management of functioning pituitary adenomas (except for prolactinomas) and non-functioning macroadenomas with visual disturbances and/or hypopituitarism. TSS combined with microscopy and intraoperative fluoroscopy, was established by Hardy in the 1960's. Moroever, endoscopic TSS has subsequently been introduced in many institutes.
Recent advancements in extended TSS approaches have greatly contributed to the management of complex pituitary adenomas. However, transcranial approaches including a simultaneous combined supra-infrasellar approach is still indicated for large/giant and multilobulated adenomas. In this study, we review the surgical treatment for pituitary adenomas from a global perspective.