2022 Volume 31 Issue 12 Pages 750-757
The efficacy and safety of intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) have been established as standard treatments in acute ischemic stroke. Various trials are being conducted to further improve the efficacy. The introduction of tenecteplase is progressing. Randomized controlled trials (RCTs) on acute stroke patients with large ischemic regions and those with strokes caused by medium vessel occlusion are also being conducted. Furthermore, results relating to combination therapy with IVT and MT, adjunctive therapy using neuroprotective agents, and medical care systems for rapid treatment, are accumulating. Therefore, further development of acute reperfusion therapy is expected to progress.
