Stem Cell Therapy for Traumatic Brain Injury : The Current and Future Perspectives

Abstract

  Stem cell therapies for the central nervous system are rapidly progressing from basic research to clinical research. Some of them have proved their safety and efficacy in the early phase of clinical trials and are moving into the late phase focusing on drug approval. In this article, we report the mode of action of stem cell therapies in the central nervous system and our recent results of phase 2a trials using intraparenchymal transplantation of mesenchymal stromal cells for patients with chronic traumatic brain injury.