Crosstalk of Research and Clinical in Functional Neurosurgery : The Future of DBS Treatment

Abstract

  In the field of functional neurosurgery, an ecosystem has been formed in which the development of therapeutic techniques has led to the elucidation of the pathophysiology of disease, and the understanding of pathophysiology has led to the development of new therapeutic techniques. Recently, a closed-loop deep brain stimulation (DBS) for Parkinson's disease was introduced to Japan for the first time, contributing to further improvement of the effectiveness of DBS treatment for Parkinson's disease. This system can collect and record local field potentials in the nuclei of the deep brain. These data can be used to elucidate the pathophysiology of Parkinson's disease, which has been difficult to do using previously utilized methods. Additionally, it is expected to lead to the development of new treatment methods for Parkinson's disease.