2023 Volume 32 Issue 4 Pages 246-253
Extraventricular neurocytoma (EVN) is a rare neuronal neoplasm that originates outside the ventricle. We report the case of a 27-year-old woman with an EVN involving the sellar region. The patient had irregular menstruation and visited our hospital for evaluation. Brain magnetic resonance imaging (MRI) revealed a solid sellar mass. She underwent endoscopic endonasal transsphenoidal surgery (eTSS), and the tumor was partially resected. Histopathological evaluation showed a glial tumor. Follow-up MRI performed 18 months later revealed enlargement of the residual lesion. The patient underwent repeat eTSS for subtotal resection of the lesion. Histopathological findings showed oligodendroglia-like cells, and immunohistochemical analysis showed cells that were immunopositive for synaptophysin and neuronal nuclei and immunonegative for glial fibrillary acidic protein and isocitrate dehydrogenase 1 R132H. The patient was definitively diagnosed with EVN. She underwent Gamma knife radiosurgery postoperatively with reduction in the size of the residual lesion.
