Cell Therapy and Rehabilitation for Traumatic Brain and Spinal Cord Injury

Abstract

  In cases of traumatic brain or spinal cord injury, initial tissue damage cannot be prevented. However, decompression, whole body management, and fixation, are used to prevent secondary damage. The prognosis for patients with traumatic brain or spinal cord injury is not necessarily good and regenerative medicine, including cell therapy may provide potential treatment options. Rehabilitation is essential for functional recovery of patients after traumatic brain or spinal cord injury and other underlying mechanisms of rehabilitation, including neuroprotection and neurogenesis present further treatment opportunities. Rehabilitation is also a critical treatment for cell therapy. Therefore, the handling and set up of rehabilitation in clinical trials of regenerative therapy is challenging. More research is required into regenerative medicine, including cell therapy and rehabilitation, to determine its clinical application as a routine treatment option in the future.