2023 Volume 32 Issue 7 Pages 443-447
Hemophilia A, a deficiency of coagulation factor Ⅷ, is the most common congenital bleeding disorder. If the family history suggests hemophilia A, instrumental delivery should be avoided to prevent bleeding complications from birth injuries. However, instrumental delivery may be considered in cases with no family history of hemophilia A. Here, we present the case of a neonatal patient with hemophilia A who underwent instrumental delivery due to the lack of a family history. The patient developed severe intracranial hemorrhage that required a craniotomy for hematoma removal. Although activated partial thromboplastin time (APTT) prolongation is the key to diagnosing hemophilia, it should be noted that APTT can be physiologically prolonged in neonates. In addition, since administration of fresh frozen plasma (FFP) alone does not have sufficient hemostatic effects in hemophilia A, care must be taken during surgery.
