Abstract
The authors report the case of 61-year-old man with intravascular lymphomatosis (neoplastic angioendoth-eliomatosis). The patient presented progressive dementia and left hemiparesis. Magnetic resonance imaging (MRI) showed multiple small infarctions in the corpus callosum and cerebral white matter. Four months after presenting the initial symptoms, he died of respiratory failure. Postmortem findings revealed a multiple intravascular proliferatlon of atypical mononuclear cells in the brain, the lungs, the adrenals, and in the other organs. The immunohistochemical findings revealed that the malignant cells were of B-lymphoid origin. In a review of the literature and including this case, only seven cases have reported on the MRI findings of this disease. Based on our findings, we feel that when marking a differential diagnosis of rapidly progressive dementia and a multifocal vascular disease, intravascular lymphomatosis should be considered among the possible causes.
