Abstract
We treated a 55-year-old female with multiple meningiomas who had undergone 3 surgeries since 1972. Although 1 meningioma (Simpson grade I) was completely extirpated in 1990, meningiomas recurred bilaterally. All 3 were completely resected (Simpson grade I). The estrogen and progesterone receptors (ER and PR) of the 3 meningiomas were measured by enzyme immunoassay. One small meningioma was ER positive, and all 3 were PR positive. The PR concentration was higher in the small- or medium-sized tumors than in the large one. The possibility of antiprogesterone treatment in tumors of this type is discussed.
