Japanese Journal of Neurosurgery
Online ISSN : 2187-3100
Print ISSN : 0917-950X
ISSN-L : 0917-950X
An Epidemiological Analysis of Risk Factors of Cerebrovascular Disease(The First Report) : Hypertensive Intracerebral Hemorrhage
Motoo KUBOTAAkira YAMAURAJun-ichi ONOToru ITANINorihide TACHIIzumi NAGATAShinji SUGIMOTO
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1998 Volume 7 Issue 5 Pages 284-290

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Abstract

To evaluate the influence of genetic factors, life style and medical history on the occurrence of cerebrovascular diseases, a multicenter case-control study was performed. In this report the authors have analyzed risk factors for spontaneus intracerebral hemorrhage (ICH). A medical history of systemic hypertension was the most powerful risk factor for ICH [odds ratio (OR)12.78, contributory rate (CR) 38.5%], followed by chronic alcohol consumption (≥ 250g/week ; OR2.31, CR16.4%). Treatment of hypertension reduced the risk of an ICH. A family history of ICH was a significant risk factor in univariate analysis, but it was not independent after adjustment for hypertension and alcohol consumption. Physically active persons had a lower risk of an ICH only in a univariate analysis (OR 0.41). 'Stress control'was another important preventative factor, and remained independent after a multivariate analysis(OR 0.54, CR 15.2%).

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© 1998 The Japanese Congress of Neurological Surgeons
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