Abstract
It has been long since cerebral arteriovenous malformation (AVM) could be cured by gamma radiosurgery. In this study, it has been found that the complete obliteration of AVM by radiosurgery is depended on the factors such as the size of the nidus, the marginal dose, the location and the age of patients. It is also ture that higher the marginal dose, higher the obliteration rate and also higher the risk of radiation injury. Therefore the marginal dose has to be limited by the radiosensitivity (tolerance) of surrounding brain, which means the obliteration rate is largely dependend on the location of AVM. The definition of the eloquent area of AVM by microsurgery is based upon the anatomical and functional importance of the brain. However, the eloquency in radiosurgery is different in that it depends upon radiosensitivity of the surounding brain around AVM. From this definition, the most eloquent area by radiosurgery is brain around the optic pathway, followed by cochlear nerve, other cranial nerves, brain stem and basal ganglia-thalamus.
