Effects and side effects of Duloxetine in our case

Abstract

Duloxetine was administered at a daily dose of 20 to 60 mg to 164 patients with chronic low back pain and 53 patients with knee joint osteoarthritis to assess its efficacy. The pain intensity was graded on a scale of 0 (no pain) to 10 (pain intensity equivalent to that prior to the duloxetine administration). Among the 164 patients with chronic low back pain, the visual analogue scale (VAS) score for pain intensity was 10 in 13 patients (no pain alleviation), and 0 in 24 patients (complete relief). Among the 53 patients with knee joint osteoarthritis, the score was 10 in three patients (no pain alleviation), 0 in one patient (complete relief), and 1 in six patients (near-complete relief). Duloxetine was considered to be useful as it exerted some degree of efficacy.