Association between serum 25-hydroxyvitamin D levels and physical activity in patients with primary osteoporosis

Abstract

Serum 25-hydroxyvitamin D (25(OH)D) levels were determined in female patients over 60 years of age diagnosed as having primary osteoporosis, and the data obtained were analyzed to explore the associations between the serum 25(OH)D levels and such factors as the risk of fragility fractures and risk of deterioration of physical activity levels. The percentage of patients with serum 25(OH)D levels in the normal range was 1.9%. Depression of physical activity was frequently seen among patients with fragility fractures and those with severe 25(OH)D deficiency. The present results show the importance of aggressive orthopedic interventions, such as exploration of any risk factors for fragility fractures by X-ray examinations, and locomotive organ rehabilitation, in addition to vitamin D supplementation in patients with osteoporosis.