2011 Volume 64 Issue 3 Pages 178-184
A 70-year-old man complained of constipation. After various examinations he was diagnosed with unresectable rectal cancer with direct invasion to the prostate and remote lymph node metastasis. Sigmoid colostomy was performed, and he was treated with chemotherapy consisting of levofolinate/5-fluorouracil/irinotecan (FOLFIRI). After completion of 14 courses of chemotherapy, bevacizumab was added to FOLFIRI. However, the patient developed grade-2 hypertension and kidney dysfunction after completion of four courses so bevacizumab was discontinued and four courses of FOLFIRI were administered. Abdominal CT of the primary tumor suggested that the patient had progressive disease, but PET-CT did not demonstrate remote metastasis.
The Hartmann operation was performed, and pathological evaluation of resected specimens showed complete regression of both the tumor and lymph node metastasis.
