2020 Volume 73 Issue 5 Pages 202-208
A 32-year-old woman visited our hospital complaining of bloody stool. Total colonoscopy revealed an 18-mm Isp tumor in the sigmoid colon, and endoscopic resection was performed. The histopathological findings confirmed a well-differentiated adenocarcinoma that had invaded the submucosal layer, and part of the tumor contained micropapillary carcinoma (MPC). In addition, positive lymphatic invasion into the submucosa was seen, and additional surgery was performed for further resection together with lymph node dissection. Regional lymph node metastasis was positive. MPC is an entity that has been proposed as a variant of breast cancer with high malignancy, and has a poor prognosis because it is associated with a high incidence of lymphatic invasion and lymph node metastasis. Colorectal cancer with MPC is considered to have a higher degree of malignancy than normal colorectal cancer, but diagnosis of MPC is not easy, and diffusion of the MPC concept seems to be a challenge.
