Two Cases of Adenosquamous Carcinoma of the Colon Treated at Our Hospital

Abstract

We report two cases of adenosquamous carcinoma of the colon. The first case was a 45-year-old man with the diagnosis of carcinoma of the upper rectum. We performed lower anterior resection and lymph node dissection. The histopathology of the tumor demonstrated adenosquamous carcinoma and the degree of progression was pT3N2bM0 pStageIIIc. Although postoperative adjuvant chemotherapy was performed, metastasis to the lungs, pelvis, and abdominal wall was detected 9 months after the operation. Systemic chemotherapy was administered up to the fourth line of treatment. The patient received best supportive care and died 28 months after surgery. The second case was a 67-year-old man with the diagnosis of carcinoma of the transverse colon. We performed right hemicolectomy and lymph node dissection. The histopathology of the tumor demonstrated adenosquamous carcinoma and the degree of progression was pT1bN0M0 pStageI. Follow up examination at 3 months after surgery revealed multiple liver tumors. Systemic chemotherapy was started, but the tumors continued to progress. The patient received best supportive care for 9 months after the operation. We report these two cases of adenosquamous carcinoma of the colon with a review of the literature.