2003 Volume 56 Issue 2 Pages 55-61
To disclose the existing state of treatments and results of synchronous hepatic metastases from colorec-tal cancer, a multi-institutional questionnaire study was conducted in 1997. Following that study, a next study was done to reveal the conclusive results, including 5-year survival, of the registered 3, 212 cases. However, only 446 cases among the accumulated 1, 843 cases were available for analysis, due to a lack of survival data.
According to multivariate analysis for this limited study, hepatic resection was the most effective treat-ment for all stages of metastatic tumors, especially H1 stage, those metastatic numbers 3 or less, and tumor diameter 2.0 cm or under. Hepatic arterial infusion therapy was the second effective for H2 stage, H3 stage, those metastatic numbers 4 or more, and tumor diameter 2.1 cm or over. Systemic chemotherapy was some-what effective for more advanced staged cases with H3 and those metastatic numbers 5 or more.
