Analysis of Colorectal Cancer with Macroscopic Invasion into the Adjacent Organs

Abstract

We investigated 144 patients of colorectal cancer with macroscopic invasion into the adjacent organs (Si⋅Ai) to find a determinant of therapeutic choice. Primary lesions were resected in 115 cases, and in 49.6% of them, macroscopic diagnosis was consistent with histological diagnosis. The cases of Si⋅Ai were frequently detected among poorly differentiated and mucinous adenocarcinoma according to histopathological types, and the rate of consistency of macroscopic diagnosis with histologic diagnosis was high in such carcinomas. The survival rate of Si⋅Ai cases showed that the patients with a high cure rate had a good prognosis. In Cur A cases, the survival rate was similar in Si⋅Ai cases and SS⋅SE⋅A1⋅A2 cases when lymph node metastasis was n0 and n1, but the survival rate was poorer in Si⋅Ai cases than in SS⋅SE⋅A1⋅A2 cases with n2-3 metastasis. Although aggressive extensive resection should be performed in patients with Si⋅Ai, surgical therapy is not sufficient for the treatment of such cases with n2-3 metastasis.