Abstract
From April 1994 through March 2012, data from 872 consecutive adult patients undergoing off-pump CABG (OPCAB) and 590 patients undergoing on-pump CABG (ONCAB) were prospectively recorded. After propensity matching, 370 OPCAB cases and 370 ONCAB cases were included in the final analysis. The OPCAB group was associated with a significantly lower operative time (4.9 h vs 5.5 h P<0.01), increase of number of bypass grafts (3.3 vs 3.1, P<0.03), reduced rate of re-exploration for perioperative bleeding (OR 0.224, 95% CI 0.075–0.671, P=0.008) and lower rate of arterial fibrillation (OR 0.659, 95% CI 0.438–0.993, P=0.046) than the ONCAB group. However, there were no significant differences between the ONCAB and OPCAB groups with respect to the incidence of perioperative myocardial infarction, stroke or renal failure requiring dialysis. Kaplan-Meier curves were estimated at five, 10 and 15 years. No differences were observed between the groups in all-cause mortality, cardiac-cause mortality or cardiac events at the 15-year follow-up (follow-up time: 15.0 y).