Abstract
In-stent restenosis (ISR) is said to be caused by under-expanded stent, neointima, etc., which can result in late stent thrombosis. Therefore preventing restenosis is an important problem in the DES era. This report presents a case of focal thrombi-related restenosis on everolimus-eluting stent confirmed by angioscopy and optical coherence tomography. Given that the management of in-stent restenosis on drug-eluting stent (DES) has not been established, intracoronary imaging tools would play an important role in the treatment of ISR after using DES. Intracoronary imaging tools will give a more accurate diagnosis and will help in the prevention and treatment of ISR.