Development of Methodologies for Structure Determination of Biological Macromolecular Assemblies Using Synchrotron Radiation and Its Applications

Abstract

Synchrotron radiation contributed to the recent progress in protein crystallography. High brilliance and small divergence synchrotron radiation X-ray beam is indispensable to collect diffraction data from crystals of biological macromolecular assemblies. Recent advance on methodologies and technologies on protein crystallography including synchrotron radiation allows us to solve huge biological macromolecular assemblies, such as large virus particles.