Current status and future directions of the field of gene therapy, with a special focus on AAV vectors

Abstract

The presence of gene therapy is increasing in clinical field. Especially, the development of Adeno-associated virus (AAV) vectors is significant, as the capsids with specific tissue specificity are increasing. As a result, several drugs have already reached the market. In this article, I will explain the principles of gene therapy, along with the characteristics of Adeno-associated virus (AAV) and the current movements of therapeutic developments. Finally, therapeutic and preventive approaches against various infectious diseases will be discussed.