Abstract
We reviewed 171 new comers who visited “osteoporosis clinic” in our hospital between May 2005 and October 2006 to evaluate the achievements of the clinic.
130 people were diagnosed as osteoporosis.
We prescribed bisphosphonates or raloxifene for the osteoporosis patient, and added calcium preparation and vitamin D to the patient whose calcium intake was under 600mg/day.
Sixty-eight relatively active patients were treated with alendronate. The markers of bone turnover improved well and the bone mineral density (BMD) of the lumbar vertebrae rose 7.5% 1 year later.
Thirty-eight patients with underlying diseases or osteoporotic fractures were treated with risedronate. Though increase of BMD was not significant statistically, urine NTX/Cre showed significant declines, and there were only 2 patients in whom a bone fracture occurred after the treatment started.
Raloxifene was prescribed for 14 patients. Its effect was not clear in this study, but the continuation rate of taking raloxifene is high even in the patients who cannot take bisphosphonates.
These medicines are recognized effective in the “Guideline 2006 for Preventation and Management of Osteoporosis”. We will manage osteoporosis considering the condition of each patient to improve total continuation rate of taking these medicines.
