Abstract
We report a case of necrotizing fasciitis in the thigh, which was treated successfully without amputation of the leg. The patient was a 52-year-old woman who presented with right thigh pain, swelling and redness. We diagnosed necrotizing fasciitis of the thigh complicated by endotoxin shock and acute renal failure, thereby systemic management was performed. We carried out surgical debridement for the necrotizing fasciitis at the 3rd week of hospitalization, and then performed surgical free skin grafting at the 13th week. The wound healed without recurrence. At the 18th week of hospitalization, the patient was able to walk using one stick, and was discharged from hospital. Endotoxin adsorption (PMX) and continuous hemodiafiltration (CHDF) were very effective for this case in an acute stage. For the treatment of necrotizing fasciitis, surgical debridement, use of adequate antibiotics, and systemic management are important.