The Journal of the Chugoku-Shikoku Orthopaedic Association
Online ISSN : 1347-5606
Print ISSN : 0915-2695
ISSN-L : 0915-2695
Selective Intra-arterial Infusion of Chemotherapy for Ewing's Sarcoma of Lumbar Vertebra: A Case Report
Yasuhiko MOTOZU
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1992 Volume 4 Issue 2 Pages 257-260

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Abstract
We describe the case of a 19-year-old man with lower back pain, suffering from Ewing's sarcoma of the second lumbar vertebra. We treated him with intra-arterial infusion of chemotherapy with satisfactory results.
We selectively catheterized the left first, second and third lumbar arteries by the femoral route, delivering 125mg of Cisdiammine Dichloroplatinum (CDDP). The next day, he felt no lower back pain and suffered no side effects. On the Magnetic Resonance Imaging (MRI) taken two weeks later, the size of the tumor was found to have decreased in size. Three weeks later, using the same method, we delivered 130mg of CDDP and three times at three-week intervals carried out Rosen T-11 protocol by selective catheterization. A surgical excision was followed by chemotherapy. Pathohistologic evaluation proved that the tumor had become extinct.
Intra-arterial infusion of chemotherapy with CDDP is considered a useful method in the treatment of Ewing's sarcoma.
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