Abstract
This paper presents a case of fibrous osteitis due to parathyroid carcinoma, diagnosis and treatment of the disease are briefly discussed. A 67-year-old woman came to our hospital owing to low back pain and body weight loss. Finger and skull X-P showed typical subperiosteal resorption and granular demineralization. Laboratory data were as follows; serum calcium 14.6mg/dl serum phosphorus 1.6mg/dl serum alkaline phosphataze 2822IU/L, and HS-PTH 23000pg/ml. On physical examination, a small and firm nodule was noted on right anterior neck. Computerized tomography and magnetic resonance imaging showed a tumor at that site. Needle biopsy suggested group 4 malignancy. The tumor was resected en bloc and regional lymph nodes were dissected. The histological diagnosis was parathyroid carcinoma.
At the 7 month after operation, laboratory, radiographic, clinical findings indicated great improvement. Neither local recurrence nor metastasis have been observed.