Abstract
Fifteen patients with lumber spinal stenosis were treated with Cirostazol, a vasodilator, orally administrated at a dosage of 200mg/day for 4 weeks. Clinical effects were evaluated by scoring of low back pain, leg pain, numbness, cold sensation, sensory disturbance, muscle weakness, gait disturbance and total JOA score. The hemodynamic effects on the legs were studied using thermography. Circulatory improvement was noted in 13 patients (86.7%) and neurological improvement in 12 patients (80.0%). Clinical effects were found to be correlated with hemodynamic effects which were characterized by increase of temperature in the leg principally within the foot. Clinical improvement obtained by Cirostazol for the patients with lumbar spinal stenosis was considered to be provied by vasodilatative hemodynamic effects on nerve lesions and the secondary circulatory disturbance in the legs.
