Abstract
A 20-year-old female broke her right femoral shaft, right patella, and bilateral distal radius in a traffic accident. Osteosynthesis was performed on her right femur and right patella using an intramedullary rod and a tension band wiring. Four weeks after the operation, the myositis ossificans was detected in the right quadriceps muscle at the fracture site. Despite the limitations on exercise of the knee joint and icing of the thigh around the ossification lesion, progression of ossification was observed on X-ray. Disodium Etidronate (EHDP, 400mg/day) was administered for 8 weeks continually. The ossification area was reduced after EHDP administration and bone union at the fracture site was completed without delay. Basal on this experience, we concluded that bone union in patients with fractures is not disturbed by the EHDP administration at the usual dose for the treatment of osteoporosis (200mg/day).
