Abstract
The aim of this study is to investigate effects of laser irradiation and acidulated phosphate fluoride on dentine remineralization. Demineralized human dentine samples were treated with or without APF and subsequently with or without laser irradiation. After these treatments, all dentine samples were remineralized in vitro in a 20 mM/l HEPES buffer containing 1.5mM/l calcium, 0.9mM/l phosphate and 2 ppm fluoride for 2 weeks. The results showed that 1) laser irradiation without APF reduced hyper -remineralization at the surface and recovered the lesion depth more significantly than in the control; 2) APF treatment enhanced remineralization strongly and inhibited hyper-remineralization; 3) in the case of APF treatment, laser effects were not observable because of the large effects of APF on remineralization.