Abstract
Gingival crevicular fluid (GCF) contains various biological materials that could reflect microbial challenge and the host response in periodontal tissue. We investigated the utilization of laboratory tests that could analyze many biochemical materials in many samples of GCF obtained in the workplace. We employed 12 biochemical tests of GCF: hemoglobin, albumin, transferrin, α_1-antitrypsin, IgG, IgA, IgM, fibronectin, PMN-elastase, myeloperoxidase, lactoferrin and lysozyme. We also employed 7 periodontal tests: supragingival plaque, gingival inflammation, pocket depth, attachment loss, dental calculus, bleeding on probing and loss of alveolar bone. GCF was taken from 93 periodontal sites of 32 workers. Each variable of the biochemical tests showed significant correlations with more than one variable of the periodontal tests. In total, significant and positive correlations were found in 26 sets of the biochemical and periodontal variables. Principal component analysis of biochemical tests extracted two principal components, and each score of the components was correlated significantly with three periodontal variables. Factor analysis using all variables computed two groups of the biochemical tests apart from three groups of the periodontal tests. These results suggest that selection or integration of biochemical variables could estimate periodontal condition and that information of biochemical tests may be different from that of periodontal tests, and thus indicate that laboratory tests of GCF in the workplace could offer various information for periodontal health of workers.
