EFFECT OF SOME FACTORS ON BINDING OF PAROTID SALIVA BASIC AND PROLINE-RICH GLYCOPROTEIN TO ORAL STREPTOCOCCI

Abstract

The binding of basic and proline-rich glycoprotein from human parotid saliva to S. mitis ATCC 9811 was specifically inhibited by D-galactose and sugars containing _D-galactose residue at a non-reducing terminal, such as lactose and N-acetyllactosamine. By both the heating and trypsin treatment on cell surface, the binding ability was remarkably reduced.