The Evaluation ofin vitroCariogenicity of Transgalactosylated Oligosaccharide

Abstract

In vitrocariogenicity of transgalactosylated oligosaccharide (TOS) was examined using oral streptococci. The results were as follows:
1. Purified TOS (TOS-P) was not utilized for growth and production of lactic acid by oral streptococci. The utilization value of TOS-P was lower than that of neosugar-P.
2. Association of TOS-P and TOS-50 with adherence in oral streptococci was not recognized.
3. Insoluble and soluble glucans from TOS-P and TOS-50 were not produced by GTase derived fromS. mutansATCC 25175 andS. sobrinusATCC 33478.
These results indicate that TOS is useful as a non-cariogenic sugar.