Determination of Carbendazim and Thiabendazole in River Sediment Sample using Liquid Chromatography/electrospray Tandem Mass Spectrometry

Abstract

Carbendazim (MBC) and thiabendazole (TBZ) in river sediments were determined by a liquid chromatograph/tandem mass spectrometer equipped with an electrospray ionization interface (LC/ESI-MS/MS) . A simple and rapid procedure using ultrasonic extraction and solid-phase extraction was evaluated to minimize the ion-suppression. The proposed methodology proved its applicability to sediment samples. Mean recovery of an internal standard MBC-d3, spiked to the ultrasonic extract was 64.0 %, with the relative standard deviation of 6.0 %. The corrected recoveries of MBC and TBZ for sediment spiked at 5 ng/g were 92.9 % and 95.6 %, respectively. Detection limits (S/N =3) of 0.06 ng/g for MBC and 0.07 ng/g for TBZ in sediment have been achieved.