Trace Analysis of Environmental Chemicals by Liquid Chromatography/Mass Spectrometry
2002 Volume 12 Issue 1 Pages 45-62
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2002 Volume 12 Issue 1 Pages 45-62
Recently, liquid chromatography-mass spectrometric determination of trace environmental pollutants has been significantly improved by the progress of atmospheric pressure chemical ionization (APCI) and electro spray ionization (ESI) . This review describes the advance of environmental analysis by liquid chromatography-mass spectrometry (LC/MS), based on 336 literatures published from 1995 to 2001. Total number of chemical substances listed in this review is 384, including agricultural chemicals (55%) and others (45%) such as nonionic surfactants and their metabolites, phenols, MX, carbonyl compounds, and estradiol and related compounds. Relationship between chemical structure and sensitivity in LC/MS is discussed and several examples of environmental analysis by LC/MS are also introduced.
