A 22-year follow-up study of the factor related to the onset of osteoarthritis of the knee and sagittal alignment of spine related to the progression of osteoarthritis of the knee

Abstract

The purpose of this study is to investigate the parameter of lower limbs related to the onset of knee osteoarthritis and reveal the longitudinal change of spinal alignment related to the progression of knee osteoarthritis during 22-years. A population register was used to recruit adult volunteers for a health screening program from 1992-1997, and the final follow-up was performed from 2015-2017. The final total of 58 volunteers were included. Current longitudinal study followed up for 22 years revealed medial proximal tibial angle was the factor related to the onset of knee osteoarthritis. Moreover, it is indicated sagittal vertical axis was related to a progression of knee osteoarthritis.