Error-prone Gene mucAB Variants in Escherichia coli Plasmids from Japanese Donors

Hiroshi Tanooka; Kouichi Tatsumi; Hideo Tsuji; Takahiro Ochiya; Hideo Hirokawa; Tomotari Mitsuoka

doi:10.3123/jemsge.31.119

SHORT COMMUNICATION

Error-prone Gene mucAB Variants in Escherichia coli Plasmids from Japanese Donors

Hiroshi Tanooka, Kouichi Tatsumi, Hideo Tsuji, Takahiro Ochiya, Hideo Hirokawa, Tomotari Mitsuoka

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Keywords: error-prone gene, mucAB, Japanese E. coli plasmid

JOURNAL FREE ACCESS

2009 Volume 31 Issue 4 Pages 119-122

DOI https://doi.org/10.3123/jemsge.31.119

Details

Abstract

Variants of the error-prone gene, mucAB, were found in Escherichia coli plasmids from 3 out of 63 healthy Japanese donors. As compared with mucAB of pKM101, one contained unaltered mucA only, while two others contained full-sized, mutated mucAB with mutation-enhancing activity in E. coli. Possible interaction between bacterial plasmid genes and host humans was discussed.

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