Abstract
By structure activity relational investigation in terms of toxicity of 221 kinds of chemicals, it is suggested that heavy metals were highly toxic for human cells and Daphnia magna and phosphorous chemicals were highly toxic for Daphnia magna. There were no correlations between the toxicity parameters of 221 kinds of chemicals to HepG2 (human hepatoblastoma cells) and Daphnia magna. The parameter indicating toxicity strength to Daphnia magna was higher than that to human cells. The parameters indicating toxicity quality to Daphnia magna were very smaller than that to human cells.
